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TRAVEL & HOTELGUIDE
Supported by
a grant from Suzuken Memorial Foundation
a grant from Suzuken Memorial Foundation
Supported by
Tokyo Convention & Visitors Bureau
Tokyo Convention & Visitors Bureau
Program
APSEV Special Lecture
Language: English
APSEV Special Lecture 1
October 22nd (Thu.) 11:00am～11:40am
Room 1 (4F Hall 2&3)
- Chair
-
- Takahiro Ochiya (Department of Molecular and Cellular Medicine, Institute of Medical Science, Tokyo Medical University)
- Speaker
-
Polymeric Nanoparticles vs Extracellular Vesicles: Advantages, Limitations, and Opportunities in Drug Delivery
Joachim Kohn
(International Union of Society for Biomaterials Science and Engineering)
Language: English
APSEV Special Lecture 2
October 22nd (Thu.) 5:30pm～6:00pm
Room 1 (4F Hall 2&3)
- Chair
-
- Yusuke Yoshioka (Department of Molecular and Cellular Medicine, Institute of Medical Science, Tokyo Medical University)
- Speaker
-
Raman Spectroscopic Profiling of Cellular and Microbial Systems, and Their Exosomes
Giuseppe Pezzotti
(Kansai Medical University)
Language: English
APSEV Special Lecture 3
October 23rd (Fri.) 5:30pm～6:00pm
Room 1 (4F Hall 2&3)
- Chair
-
- Andreas Möller (The Chinese University of Hong Kong)
- Speaker
-
Extracellular Vesicles in Thalassemia: A Narrative Review from Thailand
Kovit Pattanapanyasat
(Center of Excellence for Microparticle and Exosome in Diseases, Research Department, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand)
APSEV Plenary Lecture
Language: English
APSEV Plenary Lecture 1
October 22nd (Thu.) 9:00am～9:20am
Room 1 (4F Hall 2&3)
- Chair
-
- Kirsty Danielson (University of Otago)
- Speaker
-
From Mechanism to Medicine: Linking MoA, Potency CQAs, Manufacturing, and Clinical Development of MSC-sEV Therapeutics
Sai Kiang Lim
(Paracrine Therapeutics / Dept of Surgery, YLL School of Medicine, National University of Singapore)
Language: English
APSEV Plenary Lecture 2
October 22nd (Thu.) 5:10pm～5:30pm
Room 1 (4F Hall 2&3)
- Chair
-
- Han-Yi Chou (National Taiwan University)
- Speaker
-
Emergent Properties of Extracellular Vesicles: From Cellular Dusts to Complex Extracellular Organelles Mediating Intercellular and Interkingdom Communication
Yong Song Gho
(Department of Life Sciences, Pohang University of Science and Technology (POSTECH), Pohang, Republic of Korea)
Language: English
APSEV Plenary Lecture 3
October 23rd (Fri.) 2:10pm～2:30pm
Room 1 (4F Hall 2&3)
- Chair
-
- Nguyen Thanh Liem (Vinmec Research Institute of Stem Cell and Gene Technology, VinUniversity (VRISG))
- Speaker
-
The architecture of organelles through multi-omics
David Greening
(Baker Heart and Diabetes Institute, Australia / University of Melbourne, Australia / La Trobe University, Australia)
Language: English
APSEV Plenary Lecture 4
October 23rd (Fri.) 5:10pm～5:30pm
Room 1 (4F Hall 2&3)
- Chair
-
- Sujata Mohanty (All India Institute of Medical Sciences, New Delhi)
- Speaker
-
Exosomes Across Kingdoms: From Pathogenic Messengers to Translational Opportunities
Tang-Long Shen
(National Taiwan University)
APSEV Invited Lecture
Language: English
APSEV Invited Lecture 1
October 22nd (Thu.) 9:20am～9:50am
Room 1 (4F Hall 2&3)
- Chair
-
- Saovaros Svasti (Thalassemia Research Center, Institute of Molecular Biosciences, Mahidol University)
- Speaker
-
TBD
Han-Yi Chou
(National Taiwan University)-
A Multi-Gene Urinary Extracellular Vesicle mRNA Panel as a Non-Invasive Biomarker for Prostate Cancer Detection
Manda Venkata Sasidhar
(Apollo Hospitals Educational and Research Foundation)
Language: English
APSEV Invited Lecture 2
October 22nd (Thu.) 3:00pm～3:30pm
Room 1 (4F Hall 2&3)
- Chair
-
- Koji Ueda (Division of Analytical Biochemistry, Cancer Precision Medicine Center, Japanese Foundation for Cancer Research)
- Speaker
-
Harnessing Extracellular Vesicles and Plant-Derived Extracellular Vesicles for Oral Health: Innovations and Opportunities in Malaysia
Norhayati binti Liaqat Ali Khan
(Centre of Preclinical Science Studies, Faculty of Dentistry, Universiti Teknologi MARA (UiTM), Malaysia)
Comparative safety and efficacy of intrathecal versus intranasal delivery of mesenchymal stem cell-derived extracellular vesicles in an Aβ-induced rat model of Alzheimer’s disease
Hoang Thanh Van
(Vinmec Research Institute of Stem Cell and Gene Technology, VinUniversity)
Language: English
APSEV Invited Lecture 3
October 23rd (Fri.) 10:10am～10:40am
Room 1 (4F Hall 2&3)
- Chair
-
- Norhayati binti Liaqat Ali Khan (Centre of Preclinical Science Studies, Faculty of Dentistry, Universiti Teknologi MARA (UiTM), Malaysia)
- Speaker
-
Bioengineering Extracellular Vesicles (EVs) as a Multi-modal Vaccine Platform – Preliminary Validation against Dengue
Farid Nazer Faruqu
(Universiti Malaya)-
Extracellular Vesicles in β-Thalassaemia: Mechanistic Insights into Vasculopathy and Thrombosis
Saovaros Svasti
(Thalassemia Research Center, Institute of Molecular Biosciences, Mahidol University)
Language: English
APSEV Invited Lecture 4
October 23rd (Fri.) 2:30pm～3:30pm
Room 1 (4F Hall 2&3)
- Chair
-
- Ikuhiko Nakase (Graduate School of Science, Osaka Metropolitan University)
- Manda Venkata Sasidhar (Apollo Hospitals Educational and Research Foundation)
- Speaker
-
Evaluation of the Safety and Efficacy of MSC-Derived Extracellular Vesicles for Anti-aging in Non-Human Primate Model
Nguyen Thanh Liem
(Vinmec Research Institute of Stem Cell and Gene Technology, VinUniversity (VRISG))
Disease-Associated Biology of Extracellular Vesicles Derived from Gut Commensal Bacteria: Bacterial Messages Beyond the Gut
Hitoshi Tsugawa
(Transkingdom Signaling Research Unit, Division of Host Defense Mechanism, Tokai University School of Medicine / Institute of Medical Sciences, Tokai University)
Development of a Novel Liquid Biopsy Using Mutant Proteins in Extracellular Vesicles
Koji Ueda
(Division of Analytical Biochemistry, Cancer Precision Medicine Center, Japanese Foundation for Cancer Research)
Extracellular Vesicle Biomarkers for Ovarian Cancer: Insights from the EARLY Trial
Carlos Salomon Gallo
(The University of Queensland)
APSEV Symposium
Language: English
APSEV Symposium 1：Next-Generation Platforms for Multidimensional EV Analysis Decoding EV Biology through Emerging Technologies
October 22nd (Thu.) 10:00am～11:00am
Room 1 (4F Hall 2&3)
- Chair
-
- Nao Nishida-Aoki (Global Center for Science and Engineering, Faculty of Science and Engineering, Waseda University)
- Tang-Long Shen (National Taiwan University)
- Speaker
-
Tissue-Based Multidimensional Imaging to Decode Cancer-Derived Extracellular Vesicle Transfer and Recipient Cell Responses
Nao Nishida-Aoki
(Global Center for Science and Engineering, Faculty of Science and Engineering, Waseda University)
Beyond Exosomes: The Pharmacokinetics of Co-Circulating EV Populations
Charles Pin-Kuang Lai
(Institute of Atomic and Molecular Sciences, Academia Sinica, Taiwan)
Purifying, Profiling, Probing, and Programming—Chemical Biology Investigations of Extracellular Vesicles
Hang Hubert Yin
(Tsinghua University)
Cell-resolved organ-scale mapping of EV source-recipient relationships using 3D histology techniques
Young-Gyun Park
(Korea Advanced Institute of Science and Technology)
Language: English
APSEV Symposium 2：Clinical Translation and Regulation of EV-based Therapeutics
October 22nd (Thu.) 2:00pm～3:00pm
Room 1 (4F Hall 2&3)
- Chair
-
- Yu Fujita (EVerMed, Inc / The Jikei University School of Medicine)
- Sai Kiang Lim (Paracrine Therapeutics / Dept of Surgery, YLL School of Medicine, National University of Singapore)
- Speaker
-
Chemically induced liver progenitor-derived EVs (hCLiP-EVs) for the treatment of liver fibrosis
Juntaro Matsuzaki
(Keio University Faculty of Pharmacy)
Stage-specific extracellular vesicle remodeling during dopaminergic neuron development from human fetal (GW6) floor-plate neural stem cells
Jisook Moon
(CHA University)
The safety and efficacy of nebulized mesenchymal stromal cell-derived extracellular vesicles (hUCMSC EVs) in pulmonary fibrosis from mouse model to Phase I clinical trial
Zhijie Chang
(Tsinghua University)
Insights from the Biogenesis Pathways of MSCs-sEV: A Step Towards Clinical Translation
Sujata Mohanty
(All India Institute of Medical Sciences, New Delhi)
Language: English
APSEV Symposium 3：Research advances of engineered EVs for DDS
October 22nd (Thu.) 4:10pm～5:10pm
Room 1 (4F Hall 2&3)
- Chair
-
- Masahiko Kuroda (Department of Molecular Pathology, Tokyo Medical University)
- Minh Le (National University of Singapore)
- Speaker
-
Clinical application of plant-derived extracellular vesicles as drug delivery carriers
Masahiko Kuroda
(Department of Molecular Pathology, Tokyo Medical University)
Versatile Engineering Approaches for Diverse Extracellular Vesicle Types
Minh Le
(National University of Singapore)
Engineering of Let-7a-Enriched Extracellular Vesicles for Attenuating Peritoneal Fibrosis Induced by Peritoneal Dialysis
Chi-Ying Huang
(National Yang Ming Chiao Tung University)
Exosomes as Predictive Biomarkers for ICI Therapy: From Nanoscale Engineering to Clinical Application
Jiyoon Bu
(Inha University)
Language: English
APSEV Symposium 4：Nanotechnology-driven medical applications of Evs
October 23rd (Fri.) 9:10am～10:10am
Room 1 (4F Hall 2&3)
- Chair
-
- Akira Yokoi (Nagoya University Hospital)
- Jong Wook Hong (Hanyang University)
- Speaker
-
Toward the Clinical Application of Cellulose Nanofiber-Based EV Sheets
Akira Yokoi
(Nagoya University Hospital)
Nanowire-based extracellular vesicle profiling for liquid biopsy
Takao Yasui
(Nagoya University)
Status Que of Exosome Harvesting: Intactness, Yield, and Purity of Multiple Steps
Jong Wook Hong
(Hanyang University)
Decentralizing and Standardizing Blood Processing using Label-free Microfluidics for Extracellular Vesicles Isolation
Han Wei Hou
(Nanyang Technological University, Singapore)
Language: English
APSEV Symposium 5：EVs and Cancer
October 23rd (Fri.) 10:50am～11:50am
Room 1 (4F Hall 2&3)
- Chair
-
- Mitsuhiko Osaki (Division of Experimental Pathology, Faculty of Medicine, Tottori University / Chromosome Engineering Research Center, Tottori University)
- Andreas Möller (The Chinese University of Hong Kong)
- Speaker
-
The diverse roles of AMIGO2-containing extracellular vesicles in liver metastasis
Mitsuhiko Osaki
(Division of Experimental Pathology, Faculty of Medicine, Tottori University / Chromosome Engineering Research Center, Tottori University)
Bacterial Extracellular Vesicles in Tumors: Pathogenesis, Detection, and Therapeutic Strategies
Zihao Ou
(Nanfang Hospital, Southern Medical University)
Extracellular vesicle and RNA biomarkers for early detection and treatment optimisation in colorectal cancer
Kirsty Danielson
(University of Otago)
UBL3 regulates PD-L1-containing small extracellular vesicles in cancer— Statins as a potential strategy for improving cancer immunotherapy
Hiroshi Ageta
(Fujita Health University)
Language: English
APSEV Symposium 6：Exploring Extracellular Vesicle Diversity: From Mechanistic Insights to Analytical Tools
October 23rd (Fri.) 4:10pm～5:10pm
Room 1 (4F Hall 2&3)
- Chair
-
- Chitose Oneyama (Division of Cancer Cell Regulation, Aichi Cancer Center Research Institute)
- Carlos Salomon Gallo (The University of Queensland)
- Speaker
-
Balancing survival and communication: Stress-induced suppression of extracellular vesicle secretion
Chitose Oneyama
(Division of Cancer Cell Regulation, Aichi Cancer Center Research Institute)
Melanosomes, cell-type specific extracellular vesicles, are transferred from melanocytes to keratinocytes in skin pigmentation
Mitsunori Fukuda
(Laboratory of Membrane Trafficking Mechanisms, Graduate School of Life Sciences, Tohoku University)
Integrated nanosensor technologies for molecular analyses of circulating biomarkers
Huilin Shao
(National University of Singapore)
A proteomic approach for characterizing cellular interactors of extracellular vesicles.
Koshi Imami
(RIKEN Center for Integrative Medical Sciences )
Panel Discussion
Language: English
Panel Discussion：Regulatory Approaches to EV-Based Therapeutics in the Asia-Pacific Region
October 23rd (Fri.) 8:00am～9:00am
Room 1 (4F Hall 2&3)
- Chair
-
- Akiko Ishii-Watabe (National Institute of Health Sciences)
- Hang Hubert Yin (Tsinghua University)
- Speaker
-
Akiko Ishii-Watabe
(National Institute of Health Sciences)-
Yong Song Gho
(Department of Life Sciences, Pohang University of Science and Technology (POSTECH), Pohang, Republic of Korea)
Qing-Ling Fu
(The First Affiliated Hospital, Sun Yat-sen University)-
Tang-Long Shen
(National Taiwan University)
-
Sujata Mohanty
(All India Institute of Medical Sciences, New Delhi)
- Panelist
-
-
Sai Kiang Lim
(Paracrine Therapeutics / Dept of Surgery, YLL School of Medicine, National University of Singapore)
-
Carlos Salomon Gallo
(The University of Queensland)
-
Norhayati binti Liaqat Ali Khan
(Centre of Preclinical Science Studies, Faculty of Dentistry, Universiti Teknologi MARA (UiTM), Malaysia)
-
Manda Venkata Sasidhar
(Apollo Hospitals Educational and Research Foundation)
-
Saovaros Svasti
(Thalassemia Research Center, Institute of Molecular Biosciences, Mahidol University)
-
Hoang Thanh Van
(Vinmec Research Institute of Stem Cell and Gene Technology, VinUniversity)
JSEV Symposium
Language: Japanese
JSEV Symposium 1
October 22nd (Thu.) 4:10pm～5:10pm
Room 2 (4F Conference A)
- Chair
-
- Kazunari Akiyoshi (Institute for Integrated Cell-Material Science(iCeMS), Kyoto University)
- Speaker
-
Immune modulation using engineered extracellular vesicles
Tomoyoshi Yamano
(Department of Immunology, Graduate School of Medical Sciences, Kanazawa University / WPI Nano Life Science Institute NanoLSI Kanazawa University)
Extracellular Vesicles in Amyotrophic Lateral Sclerosis: Emerging Opportunities for Pathophysiological Assessment and Therapeutic Monitoring
Chris Kato
(Keio University Regenerative Medicine Research Center / Division of Neurodegenerative Disease Research, Tokyo Metropolitan Institute for Geriatrics and Gerontology)
Language: Japanese
JSEV Symposium 2
October 23rd (Fri.) 4:10pm～5:10pm
Room 2 (4F Conference A)
- Chair
-
- Yuki Takahashi (Kyoto University)
- Speaker
-
Engineering Approaches for Functional Extracellular Vesicles: Design, Modification, and Utilization
Yoshimasa Kawaguchi
(Institute for Chemical Research, Kyoto University)
Utility Evaluation and Development of Functional Engineering Technologies of Probiotic-Derived Extracellular Vesicles for Immunotherapy
Masaki Morishita
(Laboratory of Pharmaceutics, Kobe Pharmaceutical University)
JSEV Special Program
Language: Japanese
JSEV Special Program
October 23rd (Fri.) 9:10am～10:10am
Room 2 (4F Conference A)
- Chair
-
- Juntaro Matsuzaki (Keio University Faculty of Pharmacy)
- Yusuke Yoshioka (Department of Molecular and Cellular Medicine, Institute of Medical Science, Tokyo Medical University)
- Speaker
-
Bridging the Translation Gap in EV Therapeutics: A Venture Perspective
Yu Fujita
(EVerMed, Inc / The Jikei University School of Medicine)
The Challenges of EV Therapeutics from a Pharmaceutical Perspective
Kentaro Otake
(Takeda Pharmaceutical Company Limited.)
What Can EV IP Protect? — Lessons from a Decade of Rise and Fall in Exosome Therapeutics
Daisuke Muramatsu
(Minato Mirai Patent Firm)
Challenges for Quality Improvement of Extracellular Vesicles: An Analytical CRO Perspective
Orie Terai
(Sumika Chemical Analysis Service, Ltd.)
JSEV Educational seminar
Language: Japanese
JSEV Educational seminar
October 23rd (Fri.) 8:00am～9:00am
Room 2 (4F Conference A)
- Chair
-
- Kyoko Hida (Vascular Biology and Molecular Pathology, Hokkaido University Faculty of Dental Medicine)
- Speaker
-
Considerations on Extracellular Vesicles for Clinical Use
Naohiro Seo
(Department of Bioengineering, The University of Tokyo)
How extracellular vesicles can serve as drug delivery vehicles
Asako Yamayoshi
(Institute of Science Tokyo)
JSEV Oral Presentation
Language: English or Japanese (Depending on the speaker)
Oral Presentation JSEV 1
October 22nd (Thu.) 10:00am～11:00am
Room 2 (4F Conference A)
- Chair
-
- Ai Kotani (Research Institute of Microbial Diseases, Osaka University)
- Speaker
-
- Vaginal fluid extracellular vesicles for non-invasive detection of endometrial cancer Risa Hishikawa (Nagoya University Graduate School of Medicine, Obstetrics and Gynecology)
- Development of the proteogenomic liquid biopsy for bladder cancer recurrence using mutant proteins in urinary Evs Kazuma Sugimoto (Japanese Foundation for Cancer Research, Cancer Precision Medicine Center, Division of Analytical Biochemistry / Department of Urology, Graduate School of Medicine, The University of Tokyo)
- Investigation of the Anti-Scarring Effects of Extracellular Vesicles Derived from Embryonic Day 13 Murine Dermal Cells Riho Takayanagi (Department of Plastic and Reconstructive Surgery, Keio University School of Medicine)
- Cas13a-Based RNA Therapy for EML4-ALK Fusion-Positive Lung Cancer Using Plant-Derived Extracellular Vesicles Tsubasa Usui (Dept. Mol. Path., Tokyo Medical University)
- Anti-fibrotic Effect of Extracellular Vesicles Released from Oxidatively Stressed Cardiomyocytes Miku Takizawa (Department of Clinical and Diagnostic Laboratory Science, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo)
Language: English or Japanese (Depending on the speaker)
Oral Presentation JSEV 2
October 22nd (Thu.) 2:00pm～3:00pm
Room 2 (4F Conference A)
- Chair
-
- Takanori Ichiki (Department of Materials Engineering, The University of Tokyo)
- Speaker
-
- Arabidopsis DMP1 mediates tissue-to-tissue communications via extracellular vesicles under drought stress conditions Haruka Otani (Department of Biological Science and Technology, Tokyo University of Science)
- Bioengineered extracellular vesicles for hippocampal neuron-targeted nucleic acid delivery and gene expression controls Mana Yamada (Laboratory of Drug Delivery Systems, Graduate School of Pharmaceutical Sciences, Kobe Gakuin University)
- Small extracellular vesicles reprogram mesenchymal stromal cells for functional lymph node regeneration Shu Obana (Faculty of Pharmaceutical Sciences, Tokyo University of Science)
- Role of Dermal Sheath Cup cell EVs in ADMSC functional regulation and their potential for hair regeneration Ryuto Hatano (Regenerative Medicine Research & Biz. Development Dept, Frontier Business R&D Center, MIRAI Technology Institute, Shiseido Co. Ltd.)
- Membrane Lipid Disorder Links Therapeutic EV Potency Decline to Cargo Leakage and Impaired Delivery Kenichi Tamura (Waseda University, Cooperative Major in Advanced Biomedical Sciences, Department of Advanced Life Science and Medical Bioscience)
Language: English or Japanese (Depending on the speaker)
Oral Presentation JSEV 3
October 23rd (Fri.) 10:50am～11:50am
Room 2 (4F Conference A)
- Chair
-
- Kiyotaka Shiba (Japanese Foundation for Cancer Research)
- Speaker
-
- Intracellular acidification and extracellular vesicle changes in the antitumor effects of proton pump inhibition Daisuke Onoshima (Aichi Cancer Center Research Institute)
- EV microbiome links the gut microbiota to antitumor immunity Kentaro Jingushi (Laboratory of Stem Cell Regeneration and Adaptation, Graduate School of Pharmaceutical Sciences, The University of Osaka)
- Sonic Hedgehog-Containing Extra-Large Extracellular Vesicles (XLEVs) Drive Angiogenesis Yosuke Tanaka (Lab Molecular Cell Dynamics, Dept Cell Biol & Anat, Grad Sch Med, The University of Tokyo)
- hCLiP-derived extracellular vesicles drive convergent antifibrotic responses through model-distinct immune remodeling Kiminori Kimura (Tokyo Metropolitan Komagome Hospital・Department of Hepatology)
- High-Pressure Homogenization Enables Scalable Fabrication of Drug Loaded Extracellular Vesicles for Cancer Therapy Tatsuya Fukuta (Department of Physical Pharmaceutics, School of Pharmaceutical Sciences, Wakayama Medical University)
